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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
23.33
Human Site:
Y172
Identified Species:
46.67
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
Y172
V
E
K
A
R
T
L
Y
R
S
C
M
N
Q
S
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
Y172
V
E
K
A
R
T
L
Y
R
S
C
M
N
Q
S
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
P156
I
D
S
R
G
G
E
P
L
L
K
L
L
P
D
Dog
Lupus familis
XP_546737
807
92419
Y200
V
Q
K
A
K
M
L
Y
R
S
C
M
N
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
Y158
V
E
K
A
K
T
L
Y
R
S
C
M
N
Q
S
Rat
Rattus norvegicus
P0C1T0
774
89178
Y168
V
E
K
A
K
T
L
Y
R
S
C
M
N
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
P154
I
E
Q
R
D
S
L
P
L
L
E
V
L
T
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
L156
S
S
C
M
N
E
I
L
I
E
Q
R
D
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
F257
T
I
K
A
K
T
F
F
K
S
C
M
D
I
P
Honey Bee
Apis mellifera
XP_392502
776
89056
K181
E
D
N
N
A
T
L
K
A
K
M
F
Y
K
S
Nematode Worm
Caenorhab. elegans
O16796
848
97043
Y244
I
N
M
A
R
A
T
Y
R
S
C
M
N
K
T
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
Y167
E
R
K
V
K
H
F
Y
S
A
C
I
D
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
0
80
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
0
N.A.
40
20
53.3
20
P-Site Similarity:
100
100
20
93.3
N.A.
100
100
N.A.
N.A.
40
N.A.
13.3
N.A.
66.6
33.3
73.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
9
9
0
0
9
9
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
67
0
0
0
0
% C
% Asp:
0
17
0
0
9
0
0
0
0
0
0
0
25
0
9
% D
% Glu:
17
42
0
0
0
9
9
0
0
9
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
17
9
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
9
0
0
0
0
9
0
9
0
0
9
0
9
0
% I
% Lys:
0
0
59
0
42
0
0
9
9
9
9
0
0
17
0
% K
% Leu:
0
0
0
0
0
0
59
9
17
17
0
9
17
0
0
% L
% Met:
0
0
9
9
0
9
0
0
0
0
9
59
0
0
9
% M
% Asn:
0
9
9
9
9
0
0
0
0
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
17
0
0
0
0
0
9
9
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
9
0
0
42
9
% Q
% Arg:
0
9
0
17
25
0
0
0
50
0
0
9
0
0
0
% R
% Ser:
9
9
9
0
0
9
0
0
9
59
0
0
0
9
50
% S
% Thr:
9
0
0
0
0
50
9
0
0
0
0
0
0
17
9
% T
% Val:
42
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _